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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1850c698d1f2a2f553e6b5c3c46392dcb70063c025428c8369e3cb7eebefa41c' 
  AND token = 'fxQEK/54E0tAdzcXXxD5pZuX+bc3yyzIjGPWsgWmjs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}