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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f734d613f7024d7f8099acd550d55dc7d33e5c984b8c87be16966b3bb48d06e' 
  AND token = 'F+tPkxZbO15JYTDx9XYMtIKs3HzFn21uj69S5TDs91o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}