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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d93ebb1047d11a5e076bf26c1a24c31f6825b3acd061b8fbe23ff773de61367' 
  AND token = 'ttq67eJnhrOveWILSNzeHIVZUui6WzaU9gzq5O81BVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}