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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a39c65da3e359f5f87dbea14e30c46384f3e01d328555568ed85e69aef262eb6' 
  AND token = 'mgWQPgXmZZUtpqtcq5RDD7m+4zn0txHlVwkldGUo3Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}