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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e922d9242aaec1d0bd8289ef164b3a4da6617ff11cd68c76a38a71060ddd913' 
  AND token = 'BwnGpj+Sd3WGVq/p5OUDf4wn2ugB2w+gd3K8kWdjtQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}