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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aedda30f4579c1bc4b916cde426145581ca9dcf07bd4ce27c8f1cfe9bc8e401' 
  AND token = 'p0poKG9OoFJFDTlQiSfQlygCdrS6Pki6/f/MSKbXXXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}