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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd2dfb52b2f79c630e38b343b700c4fa5e74e611908285d8681dfc2005eebde' 
  AND token = '5sAOsP9hcuhUYZK5pex85B87Q20/5keceOMLSNu5j6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}