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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2460f693e86cdef4cbf6d84c520c2fc5b8bfea0999b50697b4c110757f8cb853' 
  AND token = 'nDZvWmFPPSP+6G5mRUgI9edpcSK+w/cd1Ysp5D8nxeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}