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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '917a2b0b8d06ed3e04ceec840c8c94e51c2472dbbc20dcbf456ddeb734629d54' 
  AND token = 'QtbH/XYpu75pAoKoHUTXUjczP6QS95CB9AkietJ8VQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}