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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756a11b64b7f948ed97d0054f94e998bcda6765ef4ce1a2f2b0ed5313280a298' 
  AND token = 'NSueFXx1yjcE6F5sSuu/qkDo9A90Wevs8mAxJ2abq28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}