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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b6c86669b1ddeafd3a1acb360d0bd06a9a099603c499993129795c644a483b' 
  AND token = 'q4cKHkp22Y8AWyxkryUTV1XidFi38sEtHCp/Nqfyw1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}