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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b910649531844531acc10c0108e52a0342e75342671fc4347c851fcf7fdc579f' 
  AND token = 'AGEEI4yfe5aGF5NrRBdpbx8PWFrvpYLiv9lHwRT2ltw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}