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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1dd5d03095bdfe88be19bcd07d0224113a3c55ec7f3bb9f90ee0d22a5e588c' 
  AND token = 'HD3QqP9aGxMq88UkT5AqQyI1Ak+W9O+QPGgoaDXTDMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}