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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e3365bb941237e714a843700dea03be0c79468611341f55b90959032c486d7' 
  AND token = '46HHCmqa8ZpGS6LzOtg8BfaL7pDtu+aUls/zP0dPr14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}