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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014a9b07579f1ccc9c4b7e72277502edfb71d7f08bd69d974659534e8365037f' 
  AND token = 'Wub7nGdxhE7Konq+QHDowf/BaeLHphLRUPz3YkzddE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}