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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d7445f35e6cf6b1bb7d78e7e463afdfc0ec3f57ae1a24d8129a642e2fe8af2' 
  AND token = 'gYNCZve5dlhysR8vFq6SrqZDkLh3UWR7jEwRN3lGR+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}