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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8435a458f92a1fd4c1cb331df6ea476a97fdbd18e4d2e7d906167c1bf9c12dcc' 
  AND token = 'ym/0ZBr1Qre2VNLlFjcXfdA/E04o1LK6mcw2bqxvw4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}