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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354597bc6a41f98918903c16a390b3c52e19fba97c6909c244a4c6c605b1a2cc' 
  AND token = 'R3pe4wG1prFSvFeCiT5dx1b0HCZyq67qvRSLTo3TVhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}