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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260e9f169484273282f8711df57d81a6e543ed18f3e6c284112d58078614f2b6' 
  AND token = '0Y5nvIkqtS9JlJ+lB5mlU7PeqSQb78SatJmmLD/K8rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}