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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8859aef2801f241c0443d84a64f34396e7747b173da4199938b076c170ef3648' 
  AND token = 'D31aNiOT+bDKouu+tmJfKNWSZ20gg3PAtfVM21tA4Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}