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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0dcac13182a01bf4e063e9f727ea4a419473d3bccca8da5ebf2e0ee9c897701' 
  AND token = '6zzkbV2sPlGOICJR0wluzSl8Nx2rPCL7+bF0LGKhrhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}