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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5c8f036611144eaf48731a61d546a4159a3cbf1088857fff4bc106428769aa0' 
  AND token = 'GRxMaJBEfC0y9HlTMqlBWUAWLz934+7kTD5XGmDllkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}