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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '935ca7e5433c0ce3b3f70d498a35cc8c687503995e29f08ad1da8be11aa40997' 
  AND token = '5OkYDkkuXqxoVEb00CuyDrwGlpSn4kyr6o6QFsHeoe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}