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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6d2d584604052b455c048508b753135c919b7188419a8be38fe53709c65a89' 
  AND token = 'Wrsi9Af3uWh4E4kTs07+HtiJDPVtLAeFRkxaLZrrbJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}