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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aef9a819f31594bf285df475ee63f400b39f0348f4aba44617d207842f46697' 
  AND token = 'IJR9d+KUCLs9JmJoT88vD8jGhL6o8smACjGjePWn/WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}