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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a774790f4aad06f92ec7fc6cb3cbd920f2ac03960b2f12f46ff097783e51122' 
  AND token = 'pdNGh+PFgFywEVKUdKtaWj/S5ACT3jiSnEoH4EgQUDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}