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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb1a8ce619b5181672986a55866b340f9d7f66842cbbdf2a5fedd0a22beedb5' 
  AND token = 'HphHErdLsnxlFD7sj1B9e8Ttji6uFcly4rjJ4iux75U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}