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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6582f1f5be41036c82c0b85238f9d6f6267d3afe5ef6303ada406b2c2073b244' 
  AND token = '5QgR509a20aTllcmN4D++rpBSLGrVwor8akEgo6JUQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}