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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d9eb43a882c2f67867b6101b2621666ade76076d3a54bd3e05ab9890f181e8' 
  AND token = 'HQx646r8denn8X43iqHgmktBEymwtAlDqI2mSg8ll4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}