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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8dc72f79e4daf5b300ff85c0035046292ee94e763886bd6513645bea88514b' 
  AND token = 's2ZP2UtySScvuWI70BSX8KgncT1D4ZcB2aqu73SSEpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}