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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e37a7fa8a928f7ff6f55c7b6e9337796b79e09d6d184ddbc69614dcad268b88' 
  AND token = 'UkV+nkcdgwbvo0Sz30NjwmDbSfSnn13b0DTkUiEo+Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}