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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec64feb04c45fe3e2e9cd3f32952fc7949cac7dd88f60c008187918ef10edae2' 
  AND token = '4rj9E6w3+wURldjlav4NG7AlSdJUYdcQwNgXMGDe1Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}