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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817e00f57e7e304dc8902efcbd997976606e6bdcb229dc3fbf6823d0e58de05e' 
  AND token = '8SwGWE4KWuQtBFDdfNaI4mgZ7MdZ8aE+x3MnqhDF/8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}