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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb210f7882ca9b610e4d0d05f2bc3a6f01d0053658545c7d84061cc7c610b2e' 
  AND token = 'FRYs3Dxtv+O0pKWc3AnfLfqDbWnVarOkIsrOsxPSQ2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}