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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751d6692666f8d1921529b1f10403a8c3db4c54aebcba1550fed4c974625147e' 
  AND token = 'NXt0DVOdqjllkr1v9P1T9OWbecVTObPa3be59sUiCUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}