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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a049b0129f24b64b226876b5520c1c7c5625227ced0899ac21be7327d92f897b' 
  AND token = '5K4V8l+TWOCSK1WXPBkzmAE1ZXcxlKz8h63v5dTR3ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}