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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee4dca6bf83c1e4e4017f4799e92304fe7fd657d1de2db8ef58875bc21ef4d6' 
  AND token = '68h0gPZ3yFfj3XXj+4CDOYgd2E9ymAcKZZN2ix7g6T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}