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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86acffc2f295664f9c2ca378b898e34405ba2e986d81c60ab6786960642d4409' 
  AND token = '/TuVcRcXzQsoePfgP77vi+5GHPlYtY42IuSo9TUTnYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}