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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c9662c3c20fb0315d624118c034d0fbaf107315dad4c7156f2c63881caf8f28' 
  AND token = 'z/a2D3IohDisTU+tnTm/zv7Xr/mXxX4+anePIZ+5+Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}