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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52aae5f8ede475bd670cac3bec573e5b3fe3c8a7d4df480b62631acd60197bcf' 
  AND token = 'tvmQzB9cxp7vbJmkueiXaaR1/c1Jz1w15WWCnW10Go0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}