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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db8eda3f59528e83e19ef7fd08536c65d599514e26363997f1c80dd728a269f' 
  AND token = 'Qc0rCDkPH2zfZGYFwpwDk00HS2CtC5fSr1ODoZLTqB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}