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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e10c54197710a34e4e3150a2f2676c5e2d10becd97c9dca376a56620361584f' 
  AND token = 'riGjubz1GsfPVhmXADIl8p4VVA1rqEsU7zDh6B6gjg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}