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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cfeeba5206a087c34fe74811942134e84d21c15d41f84a7d96ee3c6d355a09b' 
  AND token = 'VpETkukr+D33heqOY/BECDn6PuxeR7/wa87S1VpJb68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}