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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8413cdc4a78ea79b1c82a6041a07aad3c79e09dcc43994139b74e215d9e47f6' 
  AND token = 'IjiC1EAx7G/zAlPrCzavXvM3v2CviqHezGZJg+TTVb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}