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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0caa43d79d20780a3443d8fb37f94e73c4b305847dcdfe9c12b8cf5feb56ca57' 
  AND token = 'WD2qsLbNUiOTGEWXRn61hUSo4+cmYKQbT4ZLHt0zXBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}