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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b279f46c425a19c802cfdfb11bb3b6cbcf9944a1da60472821368a4624263cfc' 
  AND token = '3yArnbB92Fig6tLYBo+KBmt+blNYdZE8AJFXU8X1gRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}