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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143b884b3dcd087b35d1cc5500d762bdbdfae27bed9e398e259ffc55b14fb2e9' 
  AND token = '6a0wAFVyUdk6nU2Tbz5nnF66MhMFEnRoJz5oZjYI7Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}