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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157e8cbcc109f771239427565f6b9c020b0b54cf9aa53ba3536a53f3542532c2' 
  AND token = '90TtCShNahAtS+v0NexRPygcbZ5dc+7blOlg4W6eF4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}