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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af928519c3d48ecfeae51d4d87343c1a0afeec7cebcbeee990008fdbfe652fd6' 
  AND token = 'Rl/Z6NcqOHhdsv+sjjeQJYrItULGWDjngbAHsIzoeEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}