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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535a6a13afe1911c3cb6ffd1a23c6347267aa5c6c9b8fedf9590891dfdc018fa' 
  AND token = 'Tzp0ITL3MOz6mzIaoiYkN+ekd6z/OAOJXDdQaQLllCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}